Quinolines and derivatives
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Filtered Search Results
TARGETMOL CHEMICALS INC MAK-683 HYDROCHLORIDE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg and bulk. Please contact Fisher for quotes. MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED) (patent US20160176882 A1 compound example 2). MAK683 exhibits IC50s of 59 26 89 nM in EED Alphascreen binding ELISA and LC-MS assay. purity: 98%
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Apexbio Technology LLC IAA-94 54197-31-8 10mg
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IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
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TARGETMOL CHEMICALS INC AMINAFTONE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Aminaftone a derivative of 4-aminobenzoic acid inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis. purity: 99%
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Ambeed Methyl 5bromo2fluorobenzoate
Methyl 5-bromo-2-fluorobenzoate, 57381-59-6, 98%
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Medchemexpress LLC LM11A-31 50mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 50 MG
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LM11A-31 is a small-molecule, non-peptide ligand of the p75 neurotrophin receptor (p75NTR) that acts as a proNGF antagonist. It is brain-penetrant and has been shown to block p75-mediated cell death and to reverse cholinergic neurite dystrophy in preclinical Alzheimer's disease models, and is supplied for research use.
- Non-peptide p75 neurotrophin receptor ligand
- Acts as a proNGF antagonist and blocks p75-mediated cell death
- Brain-penetrant and orally active in preclinical models
- Documented activity in Alzheimer's disease models
- Provided with analytical documentation such as COA, H-NMR, and LC-MS
- High reported purity for research applications
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Cayman Chemical 4-HydroxyquInolIn 10g
A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
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Sigma Aldrich Fine Chemicals Biosciences Ethyl lactate natural 98 f5KG
Ethyl lactate is a major volatile flavor compound identified in Chinese Luzhou-flavor type liquor.
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Medchemexpress LLC Pacma 31 | 1401089-31-3 | 99.3% | 430.47 g·mol⁻1 | C21H22N2O6S | 100 MG
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PACMA 31 is an irreversible small-molecule inhibitor of protein disulfide isomerase (PDI) used in biochemical and cellular research. It covalently modifies active-site cysteines, has shown tumor-targeting activity in preclinical studies, and contains an alkyne moiety that enables copper-catalyzed azide-alkyne cycloaddition for conjugation and probe development.
- Irreversible inhibitor of protein disulfide isomerase for biochemical and cellular assays.
- Forms covalent bond with active-site cysteines for sustained target engagement.
- Contains an alkyne group suitable for click chemistry conjugation.
- High purity suitable for research use.
- Available in multiple pack sizes for flexible experimental needs.
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Apexbio Technology LLC Ro 31-8220 125314-64-9 50mg
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Ro 31-8220 (CAS 125314-64-9) is a potent and selective inhibitor of protein kinase C (PKC) targeting isoforms PKC- (IC50 5 nM) PKC- I (24 nM) PKC- II (14 nM) PKC- (27 nM) and PKC- (24 nM) PKC is a Ca2 and phospholipid-dependent serine/threonine kinase involved in signaling pathways regulating cell proliferation and malignancy Ro 31-8220 modulates downstream signaling by inducing c-Jun expression and activating JNK1 while inhibiting MKP-1 and c-Fos expression independent of PKC activity In immunological studies it suppresses IL-2 production (IC50 80 nM) T cell proliferation (IC50 350 nM) and CD25 expression indicating inhibition of both early and late T cell activation Ro 31-8220 is widely utilized in cellular and molecular studies to dissect PKC-dependent and independent signaling mechanisms
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Ambeed 2 4Bromophenyl isoindoline1 3d
2-(4-Bromophenyl)isoindoline-1,3-dione, 40101-31-3, 98%
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Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 25mg, CAS: 130370-60-4.
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Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development
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Chemscene ChemScene | Acridone | 100G | CS-W007771 | 0.98 | 578-95-0| MFCD00005019 | 195.22
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ChemScene | Acridone | 100G | CS-W007771 | 0.98 | 578-95-0| MFCD00005019 | 195.22
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Ambeed Dimethyl cyclohexane1 3dicarbo
Dimethyl cyclohexane-1,3-dicarboxylate, 62638-06-6, 95%
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Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 5mg, CAS: 130370-60-4.
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development
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Ambeed 4 4 Bipyridine
4,4'-Bipyridine, 553-26-4, 98%
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